NMN and NAD+ Nicotinamide Review

Can NMN Nicotinamide Mononucleotide help longevity?

As you enter into late adulthood, your health will likely be something you begin to care about more and more. While slowing the physical appearance of aging is a welcomed thought, most people will be more focused on their body’s internal health.

The idea of being able to enjoy running around with the new children in the family, or taking the dog for longer walks, can become a source of stress for some. The good news is that it’s never too late to take a preventative approach to our well-being. That said, antiaging can be a vast and confusing topic, with no clear way in which to start addressing the problems that you might not actually have yet.

While we’re not able to take away all the stress from your antiaging research, we can hopefully make it a little easier by using this article to introduce you to the health benefits of Nicotinamide Mononucleotide. You could also decide that resveratrol might be a less expensive alternative.

NMN Nicotinamide Mononucleotide Health Benefits.

Also known by its acronym, NMN, Nicotinamide Mononucleotide is a biochemical compound that’s naturally occurring inside our bodies. It’s found in a variety of foods such as broccoli, avocado, tomato, and cabbage. Supplementing your body with it can provide a slew of disease protection and general health benefits.

Mainly, it can help your body fight against some of the most common diseases and issues we see in people over 40 today.

Some of those problems include:

NMN and Adult diabetes

NMN is believed to address issues related to how NAD+ (see more information on NAD below) is working in our body, as well as reduce glucose metabolism and Type 2 adult diabetes. Those living with diabetes will know that the sickness is your body’s inability to regulate glucose production. This in turn causes it to spike higher than it should, with negative outcomes such as increasing the risk of cardiovascular issues.

NMN and Alzheimer’s

A study done on mice found that NMN can reverse the effects of Alzheimer’s, with the potential of seeing the same results in humans. The disease is the deterioration of the areas of the brain that control thought, language, and memories which can happen as our cells age. By taking NMN you’re improving your NAD+ levels, which can in turn address cell regeneration.

NMN and Cardiovascular issues

As one of the leading causes of adult deaths worldwide today, cardiovascular diseases are a serious matter. NMN, as explained below, has the ability to provide our cardio muscles and heart with the energy molecules they need in order to keep functioning as they should. Lower NAD+ levels, which NMN supplements can address, mean a potentially weakened heart and nonoptimal muscle function.

NMN and Obesity

As our body function decreases, so does our ability to metabolize calories faster. NMN can imitate calorie restriction, without forcing your mind to adjust to a constant state of dieting. And while this alone is not the only solution to preventing obesity, NMN can help with your weight loss goals.

NMN and Skin aging

If we consider that the signs of aging externally tend to be a reflection of internal aging, it would make sense to start from the inside out. Nicotinamide Mononucleotide can help improve and speed-up cell turnover, which could then change the look of our skin by slowing down the visible signs of getting older.

What do NMN and NAD+ have in common?

In broad strokes, NMN can help slow the aging process by increasing your NAD+ levels. NAD+ (which is actually called nicotinamide adenine dinucleotide) is a molecule found in every single one of our cells. Our bodies use this molecule to, among other things, help create the energy said cells need to work. We also use it to activate the proteins our body needs to heal damaged DNA.

As we age our body isn’t able to produce as much NAD+ anymore, meaning that we start to see noticeable signs of aging both inside and outside our bodies. However, NMN has the ability to increase NAD+ levels and return some of that energy to our depleted cells.

It’s a downward spiral. As we age, we produce less NAD+. And the less NAD+ we have, the more we age.

Check out the NAD health benefit research links at the bottom of the page.

What can Nicotinamide Mononucleotide do for your sirtuins?

Sirtuin activation is the other half of the work NMN can do. As a family of proteins that has the ability to regulate cellular health, sirtuin modulation is a key process within our bodies to maintain proper function and balance.

The problem is that sirtuins don’t work without the existence of NAD+. This is why supplementing your body with NMN can be so helpful in preventing aging as much as possible, and the diseases that can come along with the passage of time.

Another factor to keep in mind is that once NAD+ and sirtuins come into contact with each other, NAD+ is no longer able to keep supplying more benefits. This means that our body should technically keep making NAD+ in order to continue to regenerate our cells properly. But, as we now know, when we age we stop naturally producing the same amount of NAD+ as we once did. This is where Nicotinamide Mononucleotide supplementation can come to the rescue.

NMN seems expensive. Is there a natural alternative?

Nicotinamide Mononucleotide isn’t the only way to activate or modulate your sirtuins. Another option to fight aging and sickness is via the use of polyphenol antioxidants gathered from what we put in and on our bodies.

Polyphenols are reducing agents with the ability to help fight oxidation and through that, activate our sirtuins. Resveratrol (found in red wine, some nuts, grapes and dark chocolate), ellagic acid (also found in some nuts, berries, and grapes), and quercetin (found in green tea, onions, apples, and grapes) are all polyphenols our bodies can use to this effect.

A muscadine health supplement which has muscadine skin powder (not just the seed) contains resveratrol, ellagic acid and quercetin polyphenols. This means muscadines can be a viable alternative supplement with similar antiaging health benefits to NMN.

Not only that, but Nicotinamide Mononucleotide can typically be quite expensive with a cost upwards of thousands of dollars a year if taken as a daily supplement. For example, Dr David Sinclair, co-Director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, (Wikipedia link) is reported to take 1 gram of NMN a day, which could cost around $600 a month from Amazon.

! NMN is also a laboratory made product.

But muscadine powder with resveratrol tends to cost significantly less while offering similar longevity and disease prevention health benefits. The Muscadinex muscadine supplement costs $29.99 per month from Amazon.

! Muscadines extract is also a completely natural product.

NMN and Resveratrol.

The muscadine is a grape variety that grows right in America’s backyard. The seed is full of antioxidants, while the skin is bursting with phenols. Phenols are where the muscadine grape stores its resveratrol, ellagic acid, and quercetin. The USA muscadine grape is also up to 100 times stronger than the regular French grapes you might be familiar with.

In fact the muscadine is America's strongest source of grape resveratrol.

No wonder that so many people who want to improve their golden years take a muscadine health supplement.

If you decide to take NMN and resveratrol, the American muscadine grape is a natural choice.

Best buys for NMN and muscadine resveratrol on Amazon.

Both NMN and Muscadine health health supplements are available on Amazon. Please click on the Amazon affiliate links below to find out more:

NMN Health supplements on Amazon.

Muscadinex health supplement on Amazon.

(By the way, ‘resveratrol’ should be in spelling bee competitions. Frequent misspellings are revestrol, reversatrol, revesterol, resveritrol, reserveratrol and reversatol.)

NMN Daily Amount & Research Links.

While this article will hopefully be a great way for you to start learning more about the benefits of Nicotinamide Mononucleotide, there’s a lot more research you can look into as well.

If you’re interested in reading more, below we’ve shared our top 4 research links about NMN health benefits. All are reputable sources backed by scientific knowledge, so you can trust you’re learning from great authorities.

#1. Dr David Sinclair reportedly takes 1 gram of NMN a day, as well as resveratrol and other supplements. Find out more about NMN side effects and dosage on this webpage.

https://www.nmn.com/precursors/nmn-benefits-side-effects-dosage

#2. A website containing peer-reviewed medical and science journals, articles, and book chapters.

https://www.sciencedirect.com/science/article/pii/S1550413116304958

#3. A website providing free access to academic research articles from around the world.

https://www.frontiersin.org/about/about-frontiers

#4. The Washington University School of Medicine’s website. Offering articles and news regarding recent scientific discoveries and breakthroughs.

https://medicine.wustl.edu/news/scientists-identify-new-fuel-delivery-route-for-cells/